"[StellARrays™] were remarkably efficient and precise in identifying Notch as a previously unrecognized signaling pathway of importance to mouse plasmacytomas, a neoplasm of mature plasma cells, a pathway that is also implicated in the pathogenesis of the human plasma cell neoplasm, multiple myeloma. The arrays quickly established that NFkB signaling pathways were activated downstream of a transgene implicated in human lymphoma and postulated to be oncogenic by constitutively activating the NFκB cascade."
Herbert C. Morse III, M.D.
Chief, Laboratory of Immunopathology
National Institute of Allergy and Infectious Diseases National Institutes of Health

"BHB has the best technology I have seen to detect subtle but real differences in gene expression that can result in profound variations in biological function. The real key is their use of the Global Pattern Recognition™ algorithm that circumvents the ambiguities caused by reliance of a single normalization control."
David V. Serreze, Ph.D.
Senior Staff Scientist
The Jackson Laboratory
Genetic Basis of Immunological Tolerance Defects Underlying Type 1 Diabetes

"I have had the opportunity to use Global Pattern Recognition™ (GPR) since 2003. For anyone doing multi-gene relative expression analysis, this is really the most reliable, easiest, and fastest way to determine statistically significant differences in expression levels without the difficult task of finding the "perfect" housekeeping gene."
Gerrit J. Bouma, Ph.D.
Assistant Professor
Department of Biomedical Sciences
Animal Reproduction and Biotechnology Laboratory
Colorado State University
Transcriptional control and cellular signaling pathways mediating mammalian fetal gonadal development and differentiation.

"My group has successfully used the real time quantitative PCR system developed by Bar Harbor Biotechnology to confirm and extend preliminary microarray data analysis in our experimental system, comparing mRNA from tolerised, immunised and naive mice. We have been pleased with the quality of the plates supplied, some of which were custom modified and have found the GPR analysis software easy to use. We chose this system because it enabled us to test for 384 selected genes from small numbers of cells (as little as 100ng cDNA). We also liked the fact that the GPR analysis, by comparing each gene with every other, offered a more rigorous test of differences in gene expression than traditional real time PCR. The system allowed us to quickly obtain reliable data and further our investigations into transplant tolerance."
Diane Scott, D.Phil
Senior Lecturer
Immunology
Imperial College London

"I feel your [PerfectCircle™] system is much more informative than the standard microarray method. Having analyzed a couple of different cell models I really did not get any good data from microarrays. StellARrays™ revealed more gene expression information."
Jun Yamaou
University of Calgary
Laboratory of Pere Santamaria, PhD
Calgary, Alberta, Canada

"Our RNA samples from corneal wound healing experiments were very small, and the process to generate them was labor intensive. The data that BHB generated from our samples was clear, consistent and very informative. Technical support was very helpful."
Leonard D. Shultz, Ph.D.
Senior Staff Scientist
The Jackson Laboratory
Development of Humanized SCID Mice and Studies of Single Gene Models for Human Hematological Diseases